Mechanism of jianxin granules in the treatment of heart failure based on proteomics and metabolomics

HIGHLIGHTS

• What: This study investigates the effects of JX granules on HF and elucidates potential underlying mechanisms through proteomic and metabolomic analyses. The authors focus on oxidative stress and PI3K/Akt-mediated apoptosis pathways to uncover their roles in the therapeutic impact of JX granules. A more detailed exploration of the upstream and downstream pathways will be the focus of the future research.
• Who: Chen Yongzhong from the All procedures and protocols were approved by the Institutional Animal Care and Use Committee of Fujian University of Traditional Chinese MedicineForty healthy male Sprague-Dawley (SD) rats (190 . . .
  

   

  

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