HIGHLIGHTS
- What: The authors performed cellular resolution imaging flow cytometry and spatial hyperplexed immunofluorescence imaging to characterize the SMe in a syngeneic mouse model of tumor resection. On the basis of these observations, the authors propose a therapeutic strategy combining local treatment with the G emC12-LNC chemotherapy-based hydrogel and systemic administration of an immunomodulatory drug to delay the onset of recurrence. This study was conducted in accordance with the Declaration of Helsinki. This study shows that surgery induces both systemic and local physiological changes in GBM-bearing mice.
- Who: Chiara Bastiancich from the (UNIVERSITY . . .
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