Feasibility of non-imaging, random-sampling second harmonic generation measurements to distinguish colon cancer

HIGHLIGHTS

  • What: The authors investigate whether non-imaging randomly sampled SHG line or point intensity measurements are sufficient to distinguish normal tissue from tumor and tumor-adjacent tissue. This study investigates to what extent scanning is necessary to obtain meaningful SHG intensity data for the purpose of colorectal cancer diagnosis. A possible explanation for the difference is that this study focused on imaging colonic mucosa, whereas the other study imaged deeper colonic structures.
  • Who: Paper and collaborators from the University of Arizona, James CWyant College of Optical Sciences, Tucson, Arizona, United States have published the research . . .

     

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