An organoid model for the therapeutic effect of hyperthermic intraperitoneal chemotherapy for colorectal cancer

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  • What: The authors aimed to assess the sensitivity of in vitro hyperthermic perfusion using five different regimens i.e. mitomycin C mitomycin C combined First Received: August Published online: November K. MD with cisplatin mitomycin C combined with 5-fluorouracil oxaliplatin and oxaliplatin combined with 5-fluorouracil. The study reveals the existence of a minimum of 60 distinct HIPEC regimens, predominantly employing oxaliplatin and mitomycin C . The aim of this study was to assess the drug responsiveness of the organoid hyperthermic perfusion model to mitomycin C hyperthermic perfusion. This study is the first to use CRC organoids . . .

     

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