Feasibility and cost-effectiveness of genetic counselling for all patients with newly diagnosed ovarian cancer: a single-centre retrospective study

HIGHLIGHTS

• What: The second aim of this study was to determine whether this testing approach increased testing costs in Switzerland compared to a model in which all patients newly diagnosed with ovarian cancer are provided with a functional homologous recombination deficiency test (myChoice CDx and Geneva), followed by genetic counselling for those with positive tests. Unlike a Dutch study that proposed a reciprocal testing strategy that combined somatic BRCA testing with somatic next-generation sequencing but did not address homologous recombination deficiency , the Bernese testing approach aims to identify patients with gBRCAmt and homologous recombination deficient ovarian tumours . . .
  

   

  

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