Synthesis of potent vasodilating agents: in silico and in vitro evaluation of 6-(4-substitutedphenyl)-3-pyridazinone derivatives as potential hydralazine analogues

HIGHLIGHTS

• What: This model showed the highest cost difference of 62.030 indicating statistical significance of the model with high predictive power > 90%.
• Who: Hypertension and colleagues from the Faculty of Pharmacy, Misr International University, Cairo, Egypt have published the Article: Synthesis of potent vasodilating agents: in silico and in vitro evaluation of 6-(4-substitutedphenyl)-3- pyridazinone derivatives as potential hydralazine analogues, in the Journal: Scientific Reports Scientific Reports
• How: The resulting data was presented in Table 3 as effective drug concentration causing 50% relaxation of the norepinephrine contraction of mice aorta rings . . .
  

   

  

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