A heatmap for expected cumulative live birth rate in preimplantation genetic testing for monogenic disorders and chromosomal structural rearrangements

HIGHLIGHTS

• What: The authors assessed the expected CLBR for women undergoing PGT based on PCR, SNP array, array CGH or NGS technologies, and the authors propose an expected CLBR below 10%, 5% and 1% as thresholds for a poor, a very poor or a futile prognosis, respectively . For continuous predictors that remained in the model, a polynomial extension was considered. The model was used to create a prognosis based on female age and AMH, and was visualized with heatmaps which may find application for counselling purposes. While the model presented in this study serves as a predictive tool . . .
  

   

  

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