Evaluation of toll-like receptor 4 (tlr4) involvement in human atrial fibrillation: a computational study

HIGHLIGHTS

• What: The authors have explored the involvement of Toll-like Receptor 4 (TLR4) in atrial fibrillation (AF) by using meta-analysis of publicly available human transcriptomic data. The aim was to identify whole-genome transcriptomic datasets that could provide insights into the gene_expression profile associated with AF. Specifically, the authors focused on selecting datasets that represented mRNA expression levels from the left atrial appendage of persistent AF patients compared to control patients with sinus rhythm. Subsequently, the authors aimed to investigate the involvement of TLR4 signalling in AF.
• Who: Paolo Fagone et al. from the . . .
  

   

  

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