Retinoic acid related orphan receptor α is a genetic modifier that rescues retinal degeneration in a mouse model of stargardt disease and dry amd

HIGHLIGHTS

• What: The authors evaluate AAV5hRORA as a modifier gene therapy for macular degeneration using the Abca4-/- mouse displaying both the clinical and molecular phenotypes of dry AMD and STGD .
• Who: M. Akula from the (UNIVERSITY) have published the research: Retinoic acid related orphan receptor α is a genetic modifier that rescues retinal degeneration in a mouse model of Stargardt disease and Dry AMD, in the Journal: (JOURNAL) of 16/05/2024
• How: The authors evaluated RORA as a potent broadspectrum modifier gene therapy for macular degeneration using the Abca4-/- mouse model.
• Future . . .
  

   

  

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