Fucoidan improves d-galactose-induced cognitive dysfunction by promoting mitochondrial biogenesis and maintaining gut microbiome homeostasis

HIGHLIGHTS

• What: The aim of this study was to demonstrate the protective effect and possible mechanisms of fucoidan in D-galactose (D-gal)-induced cognitive dysfunction. In this study, the mean fluorescence intensity of images was calculated by Image J software (version 1.8.0). The authors studied the beneficial effects of fucoidan on mitochondrial biogenesis in D-gal-exposed rats. This study showed that the APN-AMPK-SIRT1 signaling pathway is related to the Dgal-induced damage modulus mechanism.
• Who: Yan Xu et al. from the Healthy Sprague Dawley (SD) rats (, weeks, SPF, ± , g) were . . .
  

   

  

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