HIGHLIGHTS
- What: The collected data were qualitatively synthesized, with the purpose of presenting a comprehensive analysis of the roles played by IL-6 and IL-1β in the context of cardiovascular diseases. Findings Djahanpour et_al conducted a systematic review covering 17 studies and identified a strong association between elevated IL-6 and IL-8 levels and the presence of peripheral arterial disease (PAD). The review emphasizes the central role of IL-6 and IL-1β in the pathogenesis and progression of cardiovascular diseases (CVDs), with elevated levels of these cytokines consistently associated with adverse clinical outcomes, such as . . .

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