HIGHLIGHTS
- What: In view of all the above, the aim of this systematic review was to identify plant-based compounds and explore their mechanism of action in inhibiting the HSP90 protein and inducing an anticancer effect in breast cancer models. Criteria Questions to Consider Q1: Did the study clearly state aims/objectives?. Concerning plant extracts, the study showed that (i) at least six plants have been used against breast cancer models, (ii) different parts of the plants were used, and_(iii) different types of extracts were proposed. The lowest IC50 described in the studies concerned the methanolic extract . . .

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