A reduced proteomic signature in critically ill covid-19 patients determined with plasma antibody micro-array and machine learning

HIGHLIGHTS

  • What: This study has identified a reduced protein signature for COVID-19 patients that contributes to COVID-19 pathophysiology characterization and may inform the development of therapeutic interventions upon further investigation. The authors identified a novel 28-protein signature and an optimal 9-protein signature that accurately classifies COVID-19 patients from non-COVID-19 sepsis controls and healthy control subjects; however, the study has several limitations.
  • Who: Douglas D. Fraser and collaborators from the (UNIVERSITY) have published the Article: RESEARCH Open Access, in the Journal: (JOURNAL)
  • How: A pairwise comparison using cosine . . .

     

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