HIGHLIGHTS
- who: HelennbspK. Matthews and collaborators from the LaboratoryUniversity College London, Gower St, London WC E BT, UK have published the research: Changes in Ect2 Localization Couple Actomyosin-Dependent Cell Shape Changes to Mitotic Progression, in the Journal: (JOURNAL) of August/14,/2012
- what: The authors show that Ect2 also activates RhoA and its downstream effectors, Rho kinase (ROK), and myosin II, at the onset of mitosis to induce the actomyosin remodeling that drives both mitotic rounding and cortical stiffening. In the search for upstream regulators of cell rounding, the authors focused the attention on established . . .
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