The single-cell atlas of the epididymis in mice reveals the changes in epididymis function before and after sexual maturity

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  • What: CytoTRACE analysis indicates that the B3 subgroup demonstrates the highest potential for differentiation and may serve as the initiation point for basal cell differentiation, as illustrated in Figures 6G, H. Furthermore, the analysis reveals that the B1 and B4 subgroups are linked to inflammatory responses, whereas the B2, B3, and B6 subgroups are associated with antiinflammatory responses. This study examined cytological changes in epididymal cells before and after maturation at 5 and 10 weeks. The study showed that sperm maturation improves before and after epididymal maturation, enhancing antiviral and bacterial infection resistance, and gradually improving regulation . . .

     

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