Pharmacological induction of mhc-i expression in tumor cells revitalizes t cell antitumor immunity

HIGHLIGHTS

  • What: In this context, this study aims to address the challenge of low MHC-I expression on tumor cells.
  • Who: Qian Yu and collaborators from the Department Fudan University, Chongqing, China have published the article: Authorship note: QY and Y Dong contributed equally to this work. Conflict of interest: The authors have declared that no conflict of interest exists, in the Journal: (JOURNAL)

SUMMARY

    A pivotal mechanism in immune evasion is the downregulation of cell surface major histocompatibility complex class I (MHC-I), compromising T_cell-mediated killing. Human MHC-I molecules . . .

     

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