The critical role of glutamine and fatty acids in the metabolic reprogramming of anoikis-resistant melanoma cells

HIGHLIGHTS

• What: This is an open-access Article distribution or reproduction in other forums is permitted provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited in accordance with accepted academic practice. The authors demonstrate that anoikis-resistant melanoma subpopulations, obtained after three consecutive rocking exposures in suspension, show a mesenchymal phenotype with high invasive ability, associated with a metabolic reprogramming from a characteristic glycolytic metabolism toward a more oxidative metabolism based on the use of glutamine and fatty_acids. The authors used the melanoma cell lines . . .
  

   

  

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