Comparing cb1 receptor girk channel responses to receptor internalization using a kinetic imaging assay

HIGHLIGHTS

  • Who: Haley K. Andersen from the Physiology, and Neuroscience, School of Medicine Columbia, University of South Carolina, Columbia, SC have published the Article: Comparing CB1 receptor GIRK channel responses to receptor internalization using a kinetic imaging assay, in the Journal: Scientific Reports Scientific Reports
  • Future: Assessment of CB1R trafficking in response to antagonists and inverse agonists with this model system is needed.

SUMMARY

    CB1R internalization occurred 24 h after plating because the measurements depended on selection of individual AtT20-SEPCB1 cells in comparison to the GIRK channel assay, which measures the . . .

     

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