Ins1 knock-in mice for beta cell-specific gene recombination

HIGHLIGHTS

• who: Transgenic mice et al. from the Center for Integrative Genomics, University of Lausanne, Genopode Building, Lausanne, Switzerland have published the Article: Ins1 knock-in mice for beta cell-specific gene recombination, in the Journal: (JOURNAL)
• what: The authors show that Ins1Cre induce efficient and selective recombination of floxed genes in beta cells from the time of birth with no recombination in the central nervous system. The authors report an inducible Ins1CreERT2 mouse line that is capable of recombination in 60-70% of the beta cells.

SUMMARY

Pancreatic beta cells participate . . .

 



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