HIGHLIGHTS
- What: This study aimed to carry out the first meta-analysis to quantitatively analyze the diagnostic and prognostic accuracy of ALU-based cfDNA in CRC patients. The trial registers including clinicaltrials.gov and trial search.who.int/AdvSearch.aspx were used in the search strategies. ** The authors investigated the threshold impact using Spearman`s correlation coefficient.
- Who: Alfonso De Stefano and colleagues from the Foundation (IRCCS), Italy University of Naples Federico II, Italy have published the paper: Diagnostic and prognostic signi fi cance of ALU-based cell-free DNA in colorectal cancer: a systematic review . . .
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