A unique cell division protein critical for the assembly of the bacterial divisome

HIGHLIGHTS

• What: The authors report a previously unrecognized core component of the Acinetobacter baumannii divisome. The authors demonstrate that the FtsAE202K and FtsBE65A mutants effectively bypassed the need of Aeg1 by A. baumannii as did the activation variants FtsWM254I and FtsWS274G. The discovery of the new essential cell division protein has provided a new target for the development of antibacterial agents. eLife assessment This study is useful identifying several gain-of-function division variants that can suppress the elongated cell division defect phenotype caused by the depletion of Age1 (or AdvA as named other studies) a known essential . . .
  

   

  

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