Human ipsc-derived myelinating organoids and globoid cells to study krabbe disease

HIGHLIGHTS

  • What: The authors show that Kd organoids have no obvious defects in neurogenesis astrogenesis and oligodendrogenesis but manifest early myelination defects. Ethics committee review All iPSC lines belong to de-identified donors and all the procedures performed in this study were reviewed by University at Buffalo Institutional Review Board (UBIRB) (STUDY00004329 and MOD00013481) that determined that the proposed activity is not research involving human subjects. iPSC demographics and culture
  • Who: Lisa Marie P. Evans and collaborators from the University at Buffalo, Buffalo, New York, United States of America, Department of Pharmacology and have published the . . .

     

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