HIGHLIGHTS
- What: Offering unprecedented volumes of data that may pave the way for innovative therapeutic approaches aimed at rectifying T-tubule abnormalities in cardiac diseases This research attempts to summarise knowledge on the crucial role of T-tubules in both health and disease by a systematic review of recent findings and existing literature, enabling a clearer awareness of their potential as targets in therapeutic interventions for cardiac disorders. In the following section, the authors examine some newly identified elements that may play a role in the pathological remodelling of the t-tubule and dyadic structure in heart failure . . .

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