Impact of baicalin and components of scutellaria baicalensis on renal fibrosis of diabetic kidney disease

HIGHLIGHTS

• What: The authors investigated the impact of multiple components of S. baicalensis on the TGF-β/Smads signaling pathway in the renal tissues of DKD db/db mice. The authors aimed to explore the mechanisms by which BA and MIX ameliorate DKD and provide an experimental foundation for the potential clinical applications of BA and MIX. for 24 h for urine collection. This study showed that MIX enhanced lipid profiles and renal function by improving renal tubular dilation, restoring the tight arrangement of renal structures, and reducing glomerulosclerosis, basal membrane thickening, and glycogen deposition. Renal tissue fibrosis is . . .
  

   

  

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