Baicalin targeting alox15 inhibits ferroptosis of lung epithelial cells and alleviates chronic obstructive pulmonary disease

HIGHLIGHTS

  • What: The authors investigated the potential of baicalin a natural compound with anti-inflammatory properties to target and inhibit ferroptosis in lung epithelial cells thereby alleviating Overexpression of BEAS-2B cells was induced by RSL-3 an activator of ferroptosis to mimic the inflammatory environment in The study demonstrates that baicalin targeting inhibits ferroptosis of lung epithelial cells and alleviates These findings provide a basis for further research and development of baicalin-based therapies for patients with the potential to improve their clinical outcomes and quality of life. To be specific, in the experiment, BEAS-2B, a . . .

     

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