HIGHLIGHTS
- What: The paper explores the mechanisms and principles of epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK) and mesenchymal-epithelial transition (MET) of targeted therapies in LC, for instance, focusing on the development, mechanism of action, clinical significance, application status, side effects and safety evaluation of small_molecule compounds and mAbs . Older individuals are more susceptible due to the accumulation of genetic mutations and a declining immune_response. the research shows that the risk of LC increases with age, with a notable increase after age 50 .
- Who: Small molecule, compounds and Silin, Liu from the Beijing . . .
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