The pan-cancer landscape of aldo-keto reductase1b10 reveals that its expression is diminished in gastric cancer

HIGHLIGHTS

• What: The authors compared the expression of AKR1B10 in multiple types of normal tissues and cancers, evaluated the relationship of AKR1B10 expression with DNA mutation, DNA Frontiers in Immunology The analysis showed AKR1B10 expression was significantly associated with TMB in 12 types of cancers, with HNSC correlation coefficient larger than 0.2, THYM, SKCM, ESCA and READ correlation coefficient smaller than -0.2 . The analysis showed the correlation between AKR1B10 expression and various ICIs in LGG, GBM, PCPG, THCA, ACC, UVM, KICH, and TGCT, but no correlations in THYM, MESO, LUSC, ESCA, and CHOL . The study provides . . .
  

   

  

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