The bacterial metabolite, lithocholic acid, has antineoplastic effects in pancreatic adenocarcinoma

HIGHLIGHTS

• What: The authors provide evidence that antioxidants are overexpressed in pancreatic adenocarcinoma and that overexpression is associated with worse clinical outcomes. Hereby the authors demonstrate that LCA induces antineoplastic features in pancreatic adenocarcinoma cells.
• Who: Szandra Schwarcz from the (UNIVERSITY) have published the research: The bacterial metabolite, lithocholic acid, has antineoplastic effects in pancreatic adenocarcinoma, in the Journal: (JOURNAL) of 10/05/2024
• How: The authors showed that LCA induces oxidative and nitrosative stress in pancreatic adenocarcinoma cells through suppressing NRF2 and inducing iNOS which plays a key role in suppressing EMT and . . .
  

   

  

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