Unveiling the therapeutic potential of lobaria extract and its depsides/depsidones in combatting aβ42 peptides aggregation and neurotoxicity in alzheimer’s disease

HIGHLIGHTS

  • What: A molecular docking analysis was conducted to investigate the interactions between Aβ peptides and GA.
  • Who: Venkatesh Katari and colleagues from the University of Toledo, United States have published the research: Unveiling the therapeutic potential of extract and its depsides/depsidones in combatting A 42 peptides aggregation and neurotoxicity in Alzheimer s disease, in the Journal: (JOURNAL)
  • How: For the first time the authors utilized biochemical and physical techniques to explore Lobaria`s inhibitory effects on Aβ42 fibrillization and depolymerization of mature fibrils. The results showed that the aggregate reducing efficiency . . .

     

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