Microrna-restricted transgene expression in the retina

HIGHLIGHTS

  • who: Francesca Simonelli and colleagues from the Telethon Institute of and Medicine (TIGEM), Naples, Italy, Medical, Department of Pediatrics, University of Naples Federico II, Naples, Italy, Medical have published the research work: MicroRNA-Restricted Transgene Expression in the Retina, in the Journal: (JOURNAL) of July/26,/2011
  • what: With this study, the authors aimed to improve controlled transgene_expression in the retina by exploiting the post-transcriptional regulation offered by the endogenous miRNA machinery. The authors show that efficient restriction of transgene_expression can be obtained even at low vector dosages. The authors show for the first . . .

     

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