Acute neural effects of the mood stabiliser lamotrigine on emotional processing in healthy volunteers: a randomised control trial

HIGHLIGHTS

  • What: This study investigated whether lamotrigine affects neural response to emotional stimuli in healthy volunteers using a well validated fMRI paradigm known to reliably elicit amygdala activity.
  • Who: Marieke A. G. Martens from the Participants Ethical approval was granted by the University of Oxford Central University Research Ethics Committee (CUREC, /RE003) and the protocol was pre-registered with clinicaltrialsgov (NCT04396938). Thirty-six healthy adult volunteers (, men, women, mean age±years, range , to , years) recruited from the Oxfordshire community took part in this study. The flow of participants is outlined in Fig., . Participants were recruited through . . .

     

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