The extracellular matrix: a key accomplice of cancer stem cell migration, metastasis formation, and drug resistance in pdac

HIGHLIGHTS

  • who: Dan Wang et al. from the Department of General Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany have published the Article: The Extracellular Matrix: A Key Accomplice of Cancer Stem Cell Migration, Metastasis Formation, and Drug Resistance in PDAC, in the Journal: Cancers 2022, 14, 3998. of /2022/
  • what: The ECM provides a favorable environment for CSCs to survive and interact with each other, which play an important role in metastasis formation of PDAC and chemotherapy resistance.
  • how: The results showed that a combination of gemcitabine and Simtuzumab did . . .

     

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