Outflow tract formation—embryonic origins of conotruncal congenital heart disease

HIGHLIGHTS

  • who: Sonia Stefanovic et al. from the (UNIVERSITY) have published the Article: Outflow Tract Formationu2014Embryonic Origins of Conotruncal Congenital Heart Disease, in the Journal: (JOURNAL)
  • future: Future Direction and Clinical Implications How environmental influences impact the molecular mediators of cardiac OFT development has immediate clinical repercussions.

SUMMARY

    Septation of the OFT, to give rise to the base (trunk) of the aorta and pulmonary arteries, involves interactions between multiple cell types, including myocardial, endocardial and neural crest cells. The inflow tract cells of the heart tube then develop into atrial cells, pulmonary . . .

     

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