HIGHLIGHTS
- who: ISRN Bioinformatics et al. from the Department of Chemical Engineering, Bogu0306azicu0327i University, Istanbul, Turkey have published the research: Discovery of YopE Inhibitors by Pharmacophore-Based Virtual Screening and Docking, in the Journal: (JOURNAL) of 12/06/2013
- what: In this work potent drug-like inhibitors of YopE are investigated with virtual approaches. In this work, the bacterial protein toxin Yersinia outer protein E (YopE), which has been found to exert GAP activity towards RhoA, Rac1, and Cdc42 of GTPases in_vitro, is investigated. The aim of this virtual screening study was to find potent YopE . . .
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