Sumoylation in skeletal development, homeostasis, and disease

HIGHLIGHTS

  • who: Huadie Liu et al. from the Laboratory of Skeletal Biology, Department of Cell Biology, Van Andel Institute, Bostwick Ave NE, Grand Rapids, MI, USA have published the Article: SUMOylation in Skeletal Development, Homeostasis, and Disease, in the Journal: Cells 2022, 11, 2710. of /2022/
  • future: Future studies dissecting the relationship between SUMOylation and aging and tissue rejuvenation will likely also bring forth new approaches to promote skeletal health. Future studies will need to determine whether SUMOylation of DGCR8 and CLOCK is required for regulating chondrocyte differentiation and homeostasis. Because of the aforementioned pleiotropic functions . . .

     

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