Yap1 plays a protective role in suppressing free fatty acid-induced apoptosis and promoting beta-cell survival

HIGHLIGHTS

  • who: Yaoting Deng from the Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA have published the article: Yap1 plays a protective role in suppressing free fatty acid-induced apoptosis and promoting beta-cell survival, in the Journal: (JOURNAL)
  • what: The authors explored the role of Yap1 in rodent insulinoma cell lines. The authors propose a model that Yap1 activation is a critical step of cellular response to FFA signaling and activated Yap1 suppresses apoptosis through its downstream target genes such as CTGF.
  • how: To decipher the role of . . .

     

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