Mbtd and cela1 association with ethambutol resistance in mycobacterium tuberculosis: a multiomics analysis

HIGHLIGHTS

  • who: Zhuhua Wu from the Sorbonne Universitu00e9s, France Universidad Veracruzana, Mexico have published the research work: mbtD and celA1 association with ethambutol resistance in Mycobacterium tuberculosis: A multiomics analysis, in the Journal: (JOURNAL)
  • what: The authors conducted laboratory microevolution of mono-EMB-resistant Mtb in_vitro and performed multi-omics analysis of laboratory-induced EMBresistant Mtb using an integrative methylome-transcriptome- proteome assay.
  • how: The results indicated that the MICs of all anti-TB drugs except EMB remained below the WHO criteria under continuous EMB drug pressure that is no cross-resistance occurred indicating . . .

     

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