Glu289 residue in the pore-forming motif of vibrio cholerae cytolysin is important for efficient β-barrel pore formation

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• who: Anish Kumar Mondal from the (UNIVERSITY) have published the article: Glu289 residue in the pore-forming motif of Vibrio cholerae cytolysin is important for efficient u03b2-barrel pore formation, in the Journal: (JOURNAL) of April/27,/2022
• what: The authors show that a specific poreforming motif residue, E289, plays crucial regulatory roles in the pore-formation mechanism of VCC. Although the single -particle cryo-EM analysis reveals WT-like oligomeric u03b2-barrel pore formation by E289A-VCC in the membrane, the authors demonstrate that the mutant shows severely delayed kinetics in terms of pore . . .
  

   

  

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