HIGHLIGHTS
- who: Top from the Department of Obstetrics and Gynecology, Peking University Hospital, Beijing, China have published the research: Inhibition of gamma-secretase in Notch1 signaling pathway as, in the Journal: (JOURNAL)
- what: The authors show that and were highly expressed in ovarian carcinoma. The authors found the expressions of Notch1, Jagged1 and NICD in ovarian cancers were not correlated with clinicopathologic factors, which needs more specimens to be demonstrated.
- how: MTT data showed that DAPT (50 u03bcM 75 u03bcM and 100 u03bcM) inhibited the proliferation of SKOV3 and CAOV3 cell lines 24 h . . .
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