Zfp30 promotes adipogenesis through the kap1-mediated activation of a retrotransposon-derived pparg2 enhancer

HIGHLIGHTS

• who: Wanze Chen from the Institut Lausanne, SwitzerlandState University have published the Article: ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors demonstrate its critical role in adipogenesis using murine in_vitro and in_vivo models, as well as human stromal vascular fraction (SVF) cells. To validate further ZFP30`s role in enhancing Pparg expression, the authors aimed to test its activity in a setting that maintains the regulatory element-promoter interaction48. Based on these collective results, the authors propose that ZFP30 . . .
  

   

  

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