The role of sphingomyelin and ceramide in motorneuron diseases

HIGHLIGHTS

  • who: Gavin McCluskey and colleagues from the Personalised Medicine Center, School of Medicine, Ulster University, Derry , SB, UK have published the article: The Role of Sphingomyelin and Ceramide in MotorNeuron Diseases, in the Journal: (JOURNAL) of 30/08/2022
  • what: SLs, particularly SM and ceramide, play vital roles in the nervous system and are dysregulated in neurodegenerative diseases.

SUMMARY

    Patients with SMA have been shown to have dysregulated fatty_acid metabolism, Patients with SMA have been shown to have dysregulated fatty_acid metabolism, increased rates of NAFLD and increased free fatty_acid levels. SMA . . .

     

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