HIGHLIGHTS
- who: Shunzong Yuan and Guang-Hua Peng from the University of Miami, United States have published the paper: Complement C3a receptor inactivation attenuates retinal degeneration induced by oxidative damage, in the Journal: (JOURNAL)
- what: The authors assessed the roles of complement C3, its receptor C3aR and the downstream effector STAT3 in the regulation of retinal degeneration in a model of sodium iodate-induced oxidative stress using various techniques, such as gene knockout, immunofluorescence, RNA sequencing (RNAseq) and functional assays. Taken together, the results of this study demonstrate that the activation of the C3a/C3aR/STAT3 . . .
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