The key player in the pathogenesis of environmental influence of systemic lupus erythematosus: aryl hydrocarbon receptor

HIGHLIGHTS

  • who: Jingwen Wu and collaborators from the Upstate Medical University, United States have published the Article: The key player in the pathogenesis of environmental influence of systemic lupus erythematosus: Aryl hydrocarbon receptor, in the Journal: (JOURNAL)

SUMMARY

    The aryl hydrocarbon receptor (AhR) was first studied as an environmental toxicant sensor. The AhR pathway is critical in the regulation of innate and adaptive immunity, it's well established that both AhR agonists and antagonists can affect the immune system. Previous studies have shown that AhR is associated with many autoimmune diseases, including multiple_sclerosis, rheumatoid . . .

     

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