Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier

HIGHLIGHTS

  • who: SUBJECT AREAS and colleagues from the (UNIVERSITY) have published the research work: Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier, in the Journal: (JOURNAL) of 11/09/2014
  • what: The aim of this study was to modify the mucus layer to reinforce the mucus barrier. Because the transgene was driven by the Tff3 promoter, the authors investigate whether Tg mice are less susceptible to chemically induced colitis.
  • how: Tg founder mice and their progeny were fertile and preliminary data showed that the offspring of the three . . .

     

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