Inhibitory effect of the novel tyrosine kinase inhibitor dcc-2036 on triple-negative breast cancer stem cells through axl-klf5 positive feedback loop

HIGHLIGHTS

  • who: Yingying Shen from the , cells (, ×, ×, ) were suspended in DMEM and Matrigel (#354234, Corning, BD Biocoat) at a, :, ratio and were injected into the fat pads of, weeks old female BALB/C-nude mice from the Hunan SJA Laboratory Animal CoLtd (Changsha, Hunan, China). , cells (, ×, ×, ) were suspended in DMEM and injected into the fat pad of, weeks old female BALB/C mice. After , days, the site of implantation was monitored for tumor growth and tumor size was measured every , or , days. Mice were randomly assigned to control and experimental groups without investigator blinding. This animal experimentation was . . .

     

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