Structural basis for shape-selective recognition and aminoacylation of a d-armless human mitochondrial trna

HIGHLIGHTS

• who: Bernhard Kuhle from the (UNIVERSITY) have published the research: Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA, in the Journal: (JOURNAL)
• what: The authors provide insight into these longstanding questions by determining high-resolution structures of an animal mitochondrial aaRS-tRNA complex. The authors propose that constructive coevolution between mtRNAs and nuclear-encoded mt-aaRSs plays an important, previously unrecognized role, involving adaptive changes in both interaction partners.
• how: Kinetic data were analyzed using GraphPad Prism 8 (GraphPad Software Inc.). The resulting video data were . . .
  

   

  

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