The chinese herb styrax triggers pharmacokinetic herb-drug interactions via inhibiting intestinal cyp3a

HIGHLIGHTS

  • who: CYP et al. from the University College London, United Kingdom have published the paper: The Chinese herb Styrax triggers pharmacokinetic herb-drug interactions via inhibiting intestinal CYP3A, in the Journal: (JOURNAL)
  • what: In this study, all assays were tested in triplicate, while the data were shown as mean ± standard deviation (SD). In this study, the inhibitory effects of these PTAs on CYP3A were assessed in HLMs by using a CYP3A-substrate drug (midazolam) and a newly reported CYP3A4 fluorescent substrate (NEN).
  • how: To better solve these two questions two CYP3A-substrate drugs . . .

     

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