Development of efficient aav2/dj-based viral vectors to selectively downregulate the expression of neuronal or astrocytic target proteins in the rat central nervous system

HIGHLIGHTS

  • who: Luc Pellerin from the Department of Physiology, Université de, Switzerland, Laboratory of Cellular and Molecular Neurotherapies (LCMN), Department of Clinical Neurosciences, University Hospital, University of have published the research work: Development of Efficient AAV2/DJ-Based Viral Vectors to Selectively Downregulate the Expression of Neuronal or Astrocytic Target Proteins in the Rat Central Nervous System, in the Journal: (JOURNAL)
  • what: Using the same AAV serotype in_vitro and in_vivo, the authors show here that a significant and specific decrease in expression could be obtained for both MCT2 and MCT4.
  • how: Immunohistochemistry Primary and . . .

     

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