Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer

HIGHLIGHTS

• who: Tesa M. Severson from the Oncode Institute University Medical have published the paper: Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors aimed to generate a compendium of_(epi)genomic, transcriptomic and clinical data for 49 ERα-positive MBC samples to better characterize the molecular makeup of this disease. Cumulatively, the authors show that global ERα and FOXA1 chromatin binding selectivity reveals gender-specific prognostic features that successfully classify MBC patients on survival.
• future: The MLL3 histone methyltransferase . . .
  

   

  

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