Pkac is not required for the preerythrocytic stages of plasmodium berghei

HIGHLIGHTS

  • who: Plasmodium berghei et al. from the Division of Parasitology, CSIR-Central Drug Research Institute, Lucknow, India have published the research work: PKAc is not required for the preerythrocytic stages of Plasmodium berghei, in the Journal: (JOURNAL)
  • what: The PKAc gene was successfully deleted in midgut sporozoites, and the authors show that PKAc cKO sporozoites invaded hepatocytes, completed liver stage (LS) development, and formed merosomes. The authors show that PKAc is indispensable during erythrocytic stages but not required in preerythrocytic stages. This experiment was performed twice with similar results, and data from one experiment are . . .

     

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